Life Sciences

We are well known for providing specialist IP advice in biotechnology, pharmaceuticals and biosimilars, diagnostics, medical devices, bioinformatics, digital health and plant protection. Our award-winning team in life sciences is led by practitioners who have been at the forefront of the sector for decades, acting in landmark cases before the EPO and the national courts of Europe. The team consists of experienced patent attorneys, litigators, SPC experts and trademark attorneys supported by technical and high-level paralegal assistants.  

A combination of PhD degrees at leading universities, academic experience and hands-on experience within industry-leading companies, academic research, and extensive patent expertise, characterizes our life sciences team patent attorneys and enables them to solve even the most challenging problems. 

In the field of life sciences, the EPO has imposed several additional limitations on patentability of inventions such as new medical uses of known compounds, stem cell technology inventions, gene sequence inventions, new dosage regimens, diagnostic and surgical methods, plant and animal breeding methods and bred plants and animals. 

In the development of inventions either for pharmaceutical, food, feed or other applications, the issue of scope of the claims is often of major importance for the value of the patent and at the same time an issue of debate within the national patent offices. It is important to draft patent applications which contain the necessary basis to ensure appropriate protection. 

In life sciences, the claim scope which is found allowable by the EPO based on a model system is often a critical issue and the commercial product is often not yet fully envisaged at the time the invention is made. To optimize the scope of patent protection, it is necessary to consider all aspects of the invention and carefully consider the patent drafting strategy in view of the availability of data. 

Our high level of expertise in the different specific fields of life sciences ensures that these issues are taken into account at the first moment that the invention is considered in order to properly draft priority documents. 

We have an extensive team of patent attorneys and advisers who have an in-depth experience  

in the field of biotechnology. We advise our clients on the acceptable scope of biotechnological claims and the best strategy for protection within the present legal frameworks. Our patent attorneys and advisers rendering services in this field all have strong scientific backgrounds and are closely involved in monitoring the evolution of the case law in biotechnology. 

Our prominence in biotechnological patenting is also reflected by the long-standing 20 year appointment of our founding partner Dr. Ann De Clercq until summer 2023 as chair of the European Patent Professionals Institute (epi) Committee on Biotechnology. Currently our partner Dr. Koen Vanhalst represents Belgium in the epi Biotech Committee and our partner Dr. Andrej Michalik is a member for Belgium of the EPPC committee of epi. Dr. Ann De Clercq is currently Deputy Secretary and BE council member for epi.  

Protection of inventions in the plant-related sector can be sought through the breeder’s rights system (plant variety rights) or through patent protection of e.g. transgenic or gene- edited plants. Both Dr. Liesbet Paemen and Dr. Ann De Clercq started their academic careers in the transgenic plant field. Liesbet further worked at transgenic plant pioneer Plant Genetics Systems prior to becoming a patent attorney. Their team has been completed with Dr. ir. Caroline Hennin, who headed the IP department at Cropdesign (now BASF Plant Science), Dr. Annelies De Clercq who got a PhD at the Department of Plant Biotechnology of the VIB and Dr. Ann Viaene who headed the IP Department of Devgen (later Syngenta). We are also a member of CIOPORA. 

Dr. Ann De Clercq and Dr. Koen Vanhalst were previous EPO examiners in Life Sciences field and Dr. Ann De Clercq headed the patent department of Innogenetics in the human healthcare Biotech filed.  

Our team of (Belgian) Patent Attorneys has extensive experience in protecting and defending the extension of the term of patents via Supplementary Protection Certificates (SPCs) before the national patent offices. Patents pertaining to a particular medical or plant protection product can be extended by a period of not more than five years through such Supplementary protection certificates. 

Our life sciences team consists of some reputed patent attorneys with extensive experience of EPO opposition and appeal procedure work.  The emphasis is on staying at the forefront of legal developments, actively seeking feedback and engaging in debate during team meetings to develop innovative strategies for drafting, prosecution, and litigation. The goal is to maintain a reputation for providing reliable, thoughtful, and relevant advice to clients. 

Furthermore, we place importance on building strong relationships with clients. This is achieved by fostering trust through open communication and consistently delivering actions that align with the clients' needs, expectations and IP strategy. 

Additionally, we take a comprehensive approach to intellectual property (IP) matters. Patent specialists collaborate closely with the trademark and transactions teams to provide clients with a complete IP service, addressing various aspects of intellectual property protection and management. 

Overall, the focus is on delivering high-quality legal services while prioritizing client relationships and staying up to date with the latest developments in the legal field. 

Our team won three times in a row the “Opposition Procedure Firm of the Year” at LMG Life Sciences EMEA Awards in 2022, 2023 and 2024. We were awarded "Patent Attorney Firm of the Year in Belgium" at the Global IP Awards in 2024, “Belgian Prosecution Firm of the Year 2024” at the Managing IP Awards and the "Best IP Firms for Patent Prosecution” category Leading by Leaders League in 2024.


With a strong track record in providing “diligence, availability and commitment”, it is no wonder that De Clercq & Partners is heralded as the “go-to law firm for patent prosecution work in Europe”. The outfit is treasured across the continent for its “consistent provision of useful strategic advice”. Making an excellent debut, Lieve Coenegrachts is a “real benefit, bringing sound experience in patent drafting and particularly relevant strategic advice in terms of patent prosecution”. She is renowned among clientele for her “thorough knowledge when working on the patentability assessments of inventions, writing patent applications and defining future patent strategies”. The “grande dame” of the biotech sector, Ann De Clercq is celebrated as a “tour de force" on the Belgian IP scene. A “good listener”, with an “affable and approachable nature”, she is a “natural at coming up with smart and pragmatic solutions”. Clients “appreciate her professionalism, clear communication and excellent follow up” in all aspects of her work. The “very dedicated and professional” Jeffrey Gyi and Liesbet Paemen are applauded for their “highly competent, efficient, excellent service and advice” and unique ability to unravel the most complex inventions”. Sakina Bounaga and Caroline Hennin are striking litigators who bring invaluable academic prowess and specialist knowledge of science and technology to secure patrons’ business needs; they are making great strides where intellectual property meets organic, polymer and pharmaceutical chemistry. Andrej Michalík and Koen Vanhalst are highly innovative attorneys, having amassed an impressive array of experience dealing with cutting-edge biotechnology cases in the areas of regenerative therapy, genome editing, vaccines, green energy and molecular biology.

IAM Patent 1000 2024

De Clercq & Partners is one of the leading Belgian firms for patent protection and portfolio management work, particularly in the fields of biotechnology and chemistry. The firm has several experienced European patent attorneys such as Ann De Clercq, Sakina Bounaga, and Liesbet Paemen. The firm is also recommended for trade mark work. Joost Muylle is the key contact for trade mark instructions.”

Managing IP STARS Reviews 2024

Key Contacts

Ann De Clercq

Ann De Clercq, PhD

Partner, European Patent Attorney, Belgian Patent Attorney, European Patent Litigator
Read more | Ann De Clercq
Koen Vanhalst

Koen Vanhalst, PhD

European Patent Litigator, Belgian Patent Attorney, European Patent Attorney, Partner
Read more | Koen Vanhalst
Liesbet Paemen

Liesbet Paemen, PhD

Partner, European Patent Attorney, European Patent Litigator
Read more | Liesbet Paemen
Andrej Michalík

Andrej Michalík, PhD

European Patent Litigator, European Patent Attorney, Partner
Read more | Andrej Michalík
Jeffrey (Jeff) Gyi

Jeffrey (Jeff) Gyi, PhD

European Patent Attorney, European Patent Litigator
Read more | Jeffrey (Jeff) Gyi
ir. Caroline Hennin

ir. Caroline Hennin, PhD

European Patent Litigator, Belgian Patent Attorney, European Patent Attorney
Read more | ir. Caroline Hennin
ir. Kris Pappaert

ir. Kris Pappaert, PhD

European Patent Litigator, European Patent Attorney
Read more | ir. Kris Pappaert
ir. David Lesthaeghe

ir. David Lesthaeghe, PhD

European Patent Litigator, Belgian Patent Attorney, European Patent Attorney
Read more | ir. David Lesthaeghe